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Crop Protection Database – Technical information, conditions of use, application methods, resistance management and modes of action.

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InAca

ABAMECTIN + PYRETHRINS

Acaricide / Insecticide

GROUP

IRAC 6 + IRAC 3A

GROUP NAME

Copper compounds + Sulfur compounds

MoA (Mode of Action)

Protein denaturation and enzyme inactivation through copper ion release + disruption of cellular respiration and energy metabolism through sulfur action

RESISTANCE LEVEL

Medium-high

CLASSIFICATION

Contact

TYPE

Multisite

ACTIVITY

Mainly preventive

Description

Broad-spectrum contact fungicide combining two multisite active substances with complementary modes of action. Tribasic copper sulfate gradually releases copper ions (Cu²⁺), which denature proteins, disrupt essential enzymes and damage the cell membranes of fungi and bacteria. Sulfur acts by contact and through its vapor phase, interfering with cellular respiration and other metabolic processes of pathogens. It is particularly effective against powdery mildew and also provides a secondary acaricidal effect against certain mites. This combination provides excellent preventive control of numerous fungal and bacterial diseases with a very low risk of resistance development.

Application Conditions

Always apply preventively or at the first stages of disease, ensuring uniform coverage of the entire crop. Avoid applications at high temperatures (above 30–32 °C), especially because of the sulfur component, and observe incompatibilities with mineral oils. Repeat applications according to disease pressure and weather conditions.

Compatibility in Treatment Programs

Compatible with many Integrated Disease Management programs. Avoid mixing with strongly acidic or alkaline products and observe the recommended interval when using mineral oils to prevent phytotoxicity.

Cross-Resistance

No cross-resistance is known with other FRAC groups. Both copper (FRAC M01) and sulfur (FRAC M02) have multisite modes of action and present a very low risk of resistance selection.

Maximum Number of Applications

There are no specific resistance-related limitations. The number of applications depends on the crop, the approved label and the maximum copper use limits established by regulations.

Recommendations for Use

Can be integrated with site-specific fungicides within resistance management programs. The combination of two multisite fungicides provides an excellent preventive basis for reducing selection pressure on other FRAC groups.

Compatibility with Beneficial Organisms

Generally yes. It has a low impact on beneficial insects and pollinators when used according to the label. However, sulfur may adversely affect certain predatory mites if applied repeatedly or under unfavorable conditions.

Technical Notes

This combination brings together the high bactericidal and fungicidal efficacy of copper against diseases such as downy mildews, bacterial diseases and various cankers, with the excellent activity of sulfur against powdery mildew and its complementary acaricidal effect. Both belong to multisite FRAC groups (M01 and M02), making them essential tools in resistance management programs and in integrated and organic production strategies, while respecting regulatory limits on copper use.

Products Based on:

ABAMECTIN + PYRETHRINS

Related Treatments

Plantynia mobile app for plant care and the diagnosis of pests and diseases.
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